Preterm birth prevention—Time to PROGRESS beyond progesterone

نویسندگان

  • Jane E Norman
  • Phillip Bennett
چکیده

In a Perspective, Jane Norman and Phillip Bennett argue that it is time to explore alternatives to progesterone for preventing preterm birth.

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منابع مشابه

P-188: Vaginal Progesterone Effects for The Prevention of Preterm Birth and Neonatal Complications in Women at Increased Risk: A Randomized Placebo- Controlled Double-Blind Study

Background: The purpose of this study was to evaluate the effect of prophylactic vaginal progesterone in decreasing preterm birth rate and neonatal complications in a high-risk population. Materials and Methods: A randomized, double-blind, placebo- controlled study included 100 high-risk singleton pregnancies( prior preterm birth,short cervix,uterine malformations and large intramural uterine m...

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Study of progesterone for the prevention of preterm birth in twins (STOPPIT): findings from a trial-based cost-effectiveness analysis.

OBJECTIVES Preterm birth contributes to a range of healthcare problems amongst infants surmounting to sizeable healthcare costs. Twin pregnancies are at particular risk of preterm birth. The objective of this study was to assess the cost-effectiveness of vaginal progesterone gel for the prevention of preterm birth in twin pregnancies. METHODS An economic evaluation was conducted alongside a r...

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Clinical Application of Progesterone for the Prevention of Preterm Birth, 2016.

While the preterm neonate continues to benefit from improved perinatal care, the rate of preterm birth in the United States remains significant. An increasing body of scientific literature has demonstrated the benefits of maternal progesterone administration in reducing primary and recurrent preterm birth. Intramuscular hydroxyprogesterone caproate is indicated in singleton pregnancies in women...

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Comparative Study of Vaginal versus Intramuscular Progesterone in the Prevention of Preterm Delivery: A Randomized Clinical Trial

BACKGROUND Preterm birth is a worldwide health concern due to its various negative consequences. Therefore, the prevention of preterm birth is a top priority for healthcare systems in all countries. OBJECTIVE To compare the effectiveness of vaginal versus intramuscular progesterone in the prevention of preterm delivery. METHODS This randomized clinical trial was conducted at Shahid Sadoughi...

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Progesterone for the prevention of preterm birth: a systematic review.

OBJECTIVE We performed a systematic review to assess the benefits and harms of progesterone administration for the prevention of preterm birth in women and their infants. DATA SOURCES The Cochrane Controlled Trials Register was searched, and reference lists of retrieved studies were searched by hand. No date or language restrictions were placed. METHODS OF STUDY SELECTION Randomized trials ...

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2017